dnasis pro v3.0 (Hitachi Ltd)
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dnasis pro v3.0
Dnasis Pro V3.0, supplied by Hitachi Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dnasis+pro+v3%2E0/pm30594530-96-5-8
Average 90 stars, based on 1 article reviews
Dnasis Pro V3.0, supplied by Hitachi Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dnasis+pro+v3%2E0/pm30594530-96-5-8
Average 90 stars, based on 1 article reviews
dnasis pro v3.0 - by Bioz Stars,
2026-09
90/100 stars
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other:Article Title: Evaluation of all non-synonymous single nucleotide polymorphisms (SNPs) in the genes encoding human deoxyribonuclease I and I-like 3 as a functional SNP potentially implicated in autoimmunity. Article Snippet: 1 Division of Medical Genetics and Biochemistry, Faculty of Medical Sciences, University of Fukui, Japan 2 Department of Legal Medicine, Shimane University School of Medicine, Japan 3 Division of Life Sciences, Faculty of Medical Sciences, University of Fukui, Japan 4 Department of Legal Medicine, Gunma University School of Medicine, Japan 5 Department of Cardiology, Kanazawa Medical University, Ishikawa, Japan Article Title: Five non-synonymous SNPs in the gene encoding human deoxyribonuclease I-like 2 implicated in terminal differentiation of keratinocytes reduce or abolish its activity. Article Snippet: Several non-synonymous SNPs in the human deoxyribonuclease I-like 2 (DNase 1L2) gene responsible for DNA degradation during terminal differentiation of epidermal keratinocytes have been identified.. However, only limited population data are available, and furthermore the effect of these SNPs on the DNase 1L2 activity remains unknown.. Genotyping of all of the 17 SNPs was performed using the PCR-RFLP method in three ethnic groups including 14 different populations. Article Title: Functional Single Nucleotide Polymorphisms (SNPs) in the Genes Encoding the Human Deoxyribonuclease (DNase) Family Potentially Relevant to Autoimmunity. Article Snippet: Objective: To continue our previous investigations, we have extensively investigated the function of the 61, 41, and 35 non-synonymous single nucleotide polymorphisms (SNPs) in the human genes encoding DNASE1, DNASE1L3, and DNASE2, respectively, potentially relevant to autoimmune diseases.. Methods: The site-directed mutagenesis was employed to amino acid–substituted constructs corresponding to each SNP.. The COS-7 cells were transfected with each vector and DNase activity was assayed by the single radial enzyme diffusion method. Article Title: Evaluation of All Nonsynonymous Single-Nucleotide Polymorphisms in the Gene Encoding Human Deoxyribonuclease I-Like 1, Possibly Implicated in the Blocking of Endocytosis-Mediated Foreign Gene Transfer Article Snippet: Multiple alignment analyses of the amino acid sequences of animal DNase 1L1 were performed using Article Title: Seven nonsynonymous SNPs in the gene encoding human deoxyribonuclease II may serve as a functional SNP potentially implicated in autoimmune dysfunction. Article Snippet: Many nonsynonymous SNPs in the human DNase II gene (DNASE2), potentially relevant to autoimmunity in conditions such as rheumatoid arthritis, have been identified, but only limited population data are available and no studies have evaluated whether such SNPs are functional.. Genotyping of all the 15 nonsynonymous human DNase II SNPs was performed in three ethnic groups including 16 different populations using the PCR-restriction fragment length polymorphism technique.. A series of constructs corresponding to each SNP was examined. Article Title: Identification of functional SNPs potentially served as a genetic risk factor for the pathogenesis of parakeratosis in the gene encoding human deoxyribonuclease I-like 2 (DNase 1L2) implicated in terminal differentiation of keratinocytes. Article Snippet: Abbreviations:BLAST, basic local alignment search tool I-like 2; DNase 1L1, DNase I-like 1/DNase X/DNase Xib;DN MAF,minor allele frequency; RFLP, restriction fragment le interference;SRED,singleradialenzymediffusion;TREX2, t ⁎ Corresponding author at: Department of LegalMedicin Medicine, 89-1, Enya, Izumo, Shimane 693-8501, Japan.. E-mail address: htakeshi@med.shimane-u.ac.jp (H. Ta 1 Contributed equally to this study. Article Title: Increased susceptibility to oxidative stress-induced toxicological evaluation by genetically modified nrf2a-deficient zebrafish. Article Snippet: Introduction: Oxidative stress plays an important role in drug-induced toxicity.. Oxidative stress-mediated toxicities can be detected using conventional animal models but their sensitivity is insufficient, and novel models to improve susceptibility to oxidative stress have been researched.. In recent years, gene targeting methods in zebrafish have been developed, making it possible to generate homozygous null mutants. |